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Dr. Extavour has received numerous honors and awards, including the NSERC Canada, Trinity College and Edward Blake Admissions Scholarships and the Robert Philips Award for Excellence in Spanish as an undergraduate student; a graduate training fellowship of the Spanish Ministry of Science and Research as a graduate student; the EMBO Short Term Fellowship as a postdoctoral researcher, and the Ellison Medical Foundation New Scholar in Aging Award as an Assistant Professor. For her teaching and mentoring activities, she has been nominated for the Joseph R. Levenson Memorial Teaching Prize and the Harvard Graduate Women in Science and Engineering Mentoring Award.
Dr. Extavour began working on germ cell development in graduate school. In her Ph.D. thesis, she used classical Drosophila genetics to explore the genetic requirements of germ cells during development. Using clonal analysis, she showed that primordial germ cells engage in cell-cell competition prior to gametogenesis, revealing a level of natural selection that operates not only pre-zygotically, but in the very precursors of gametes themselves. This means that allele frequencies can potentially be changed from one generation to the next, not only by natural selection operating on sexually mature adult individuals, but also on the cells responsible for producing the gametes that will ultimately give rise to those individuals. Because of the critical role of germ cells not only in development but also in evolution, her subsequent work has focused on germ cell development in a comparative context.
Dr. Extavour began working on germ cell development in graduate school. In her Ph.D. thesis, she used classical Drosophila genetics to explore the genetic requirements of germ cells during development. Using clonal analysis, she showed that primordial germ cells engage in cell-cell competition prior to gametogenesis, revealing a level of natural selection that operates not only pre-zygotically, but in the very precursors of gametes themselves. This means that allele frequencies can potentially be changed from one generation to the next, not only by natural selection operating on sexually mature adult individuals, but also on the cells responsible for producing the gametes that will ultimately give rise to those individuals. Because of the critical role of germ cells not only in development but also in evolution, her subsequent work has focused on germ cell development in a comparative context.
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论文共 139 篇作者统计合作学者相似作者
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bioRxiv (Cold Spring Harbor Laboratory) (2024)
Arpita Kulkarni,Ben Ewen-Campen,Kanta Terao,Yukihisa Matsumoto, Yaolong Li,Takayuki Watanabe, Jonchee A. Kao,Swapnil S. Parhad,Guillem Ylla,Makoto Mizunami,Cassandra G. Extavour
Proceedings of the National Academy of Sciencesno. 21 (2023)
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G3 (Bethesda, Md.)no. 2 (2022)
MOLECULAR BIOLOGY AND EVOLUTIONno. 3 (2022)
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