Caroline A. Heckman - Inst Mol Med Finland FIMM, Univ Helsinki

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Designing patient-oriented combination therapies for acute myeloid leukemia based on efficacy/toxicity integration and bipartite network modeling

Mehdi Mirzaie,Elham Gholizadeh,Juho J. Miettinen, Filipp Ianevski,Tanja Ruokoranta,Jani Saarela,Mikko Manninen,Susanna Miettinen,Caroline A. Heckman,Mohieddin Jafari

Research Square (Research Square)no. 1 (2024): 11-11

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Targeting CD33+ acute myeloid leukemia with GLK-33, a lintuzumab-auristatin conjugate with a wide therapeutic window

Tero Satomaa, Henna Pynnönen,Olli Aitio, Jukka O Hiltunen, Virve Pitkänen, Tuula Lähteenmäki, Titta Kotiranta,Annamari Heiskanen, Anna-Liisa Hänninen, Ritva Niemelä,Jari Helin,Heikki Kuusanmaki,

Molecular cancer therapeutics (2024)

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Robust scoring of selective drug responses for patient-tailored therapy selection

Yingjia Chen,Liye He,Aleksandr Ianevski,Pilar Ayuda-Durán,Swapnil Potdar,Jani Saarela,Juho J. Miettinen,Sari Kytölä,Susanna Miettinen,Mikko Manninen,Caroline A. Heckman,Jorrit M. Enserink,

Nature Protocolsno. 1 (2024): 60-82

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Designing patient-oriented combination therapies for acute myeloid leukemia based on efficacy/toxicity integration and bipartite network modeling

Mehdi Mirzaie,Elham Gholizadeh,Juho J. Miettinen, Filipp Ianevski,Tanja Ruokoranta,Jani Saarela,Mikko Manninen,Susanna Miettinen,Caroline A. Heckman,Mohieddin Jafari

ONCOGENESISno. 1 (2024)

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Abstract A14: Ex vivo immune activation with the macrophage-targeting immunotherapy, anti-Clever-1 antibody bexmarilimab, in acute myeloid leukemia and myelodysplastic syndrome

Arno Ylitalo,Sofia Aakko,Heikki Kuusanmäki,Mari Björkman,Juho Jalkanen,Marie-Louise Fjällskog,Caroline A. Heckman,Maija Hollmén,Mika Kontro

Blood cancer discoveryno. 3_Supplement (2023): A14-A14

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Table S1 from Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies

Petri Pölönen,Juha Mehtonen,Jake Lin,Thomas Liuksiala, Sergei Häyrynen,Susanna Teppo,Artturi Mäkinen,Ashwini Kumar,Disha Malani, Virva Pohjolainen,Kimmo Porkka,Caroline A. Heckman,

crossref（2023）

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Table S3 from Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies

Petri Pölönen,Juha Mehtonen,Jake Lin,Thomas Liuksiala, Sergei Häyrynen,Susanna Teppo,Artturi Mäkinen,Ashwini Kumar,Disha Malani, Virva Pohjolainen,Kimmo Porkka,Caroline A. Heckman,

crossref（2023）

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S175: single-cell analysis reveals somatic tp53 mutations emerge in early progenitor cells but become enriched in the erythroid lineage in ercc6l2 disease

Laura Langohr, Ilse Kaaja,Suvi Douglas, T. H. Räisänen,Sadiksha Adhikari,Markus Vähä‐Koskela,Caroline A. Heckman,Jenni Lahtela,Ulla Wartiovaara‐Kautto,Esa Pitkänen,Outi Kilpivaara

HemaSphereno. S3 (2023): e8517818-e8517818

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The α2A-adrenergic receptor (ADRA2A) modulates susceptibility to Raynaud’s syndrome

Anniina Tervi, Markus Ramste,Erik Abner,Paul Cheng,Jacqueline M. Lane,Matthew Maher, Vilma Lammi,Satu Strausz,Trieu Nguyen, Mauro Lago Docampo,Wenduo Gu, FinnGen, Estonian biobank research team,

medRxiv (Cold Spring Harbor Laboratory) (2023)

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Data from Individualized Systems Medicine Strategy to Tailor Treatments for Patients with Chemorefractory Acute Myeloid Leukemia

Tea Pemovska,Mika Kontro,Bhagwan Yadav,Henrik Edgren,Samuli Eldfors,Agnieszka Szwajda,Henrikki Almusa,Maxim M. Bespalov,Pekka Ellonen,Erkki Elonen, Bjørn T. Gjertsen,Riikka Karjalainen,

crossref（2023）

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