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Axons are the primary target in many neurodegenerative diseases associated with both the central and peripheral nervous system. Dysfunction and degeneration of axons i.e. axonopathy, is often the earliest sign of neurodegeneration. We use molecular, cellular, biochemical, and imaging methods to investigate the cellular and molecular mechanisms of axonopathy and neurodegeneration. Our ultimate goal is to understand how impairment of axonal functions leads to neurodegenerative diseases such as Alzheimer’s disease (AD), Tauopathies, Huntington’s disease (HD), Down syndrome (DS), and Charcot-Marie-Tooth 2B (CMT2B) peripheral sensory neuropathy.
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论文共 109 篇作者统计合作学者相似作者
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Yingli Gu,Alexander Pope,Charlene Smith,Christopher Carmona,Aaron Johnstone,Linda Shi,Xuqiao Chen, Sarai Santos, Claire Cecile Bacon-Brenes,Thomas Shoff, Korbin M. Kleczko,Judith Frydman,
Sophia Barber,Veronica Gomez-Godinez, Joy Young, Abigail Wei, Sarah Chen, Anna Snissarenko, Sze Sze Chan,Chengbiao Wu,Linda Shi
JOURNAL OF BIOPHOTONICSno. 3 (2024): e202300370-e202300370
crossref(2023)
Zhiyong Ding,Peter German,Shanshan Bai,A. Srinivas Reddy,Xian-De Liu, Mianen Sun,Lijun Zhou, Xiaohua Chen,Xiaobei Zhao,Chengbiao Wu,Shuxing Zhang,Gordon B. Mills,
crossref(2023)
Journal of Alzheimer's disease : JADno. 1 (2023): 349-361
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