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Dr. Peters' research focuses on the pathogenesis and epidemiology of viral hemorrhagic fevers and other emerging viral infections. Most of the current work in the laboratory deals with Bunyaviridae (phleboviruses such as Rift Valley fever); Arenaviridae (Lassa fever, South American hemorrhagic fevers) and SARS CoV. Dr. Peters' lab is working on the phylogeny of phleboviruses (Rift Valley Fever), reassortment of their tripartite genomes, and their pathogenicity. He is developing alphavirus replicon-vectored Rift Valley fever vaccines for use in livestock and humans. Arenavirus research concentrates on the effects of infection on cellular function, particularly those molecular interactions related to vascular permeability. SARS-CoV work includes antiviral drug development, model charaterization, and interfeon interactions. Dr. Peters' laboratory is transitioning to higher hazard viral hemorrhagic fevers and will develop projects on other viruses such as tick-borne flaviviruses, highly virulent avian influenza strains, and Nipah virus, a new, highly virulent paramyxovirus.
研究兴趣
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Vaccine: X (2020): 100060-100060
Phillip R Pittman,Sarah L Norris, Elizabeth S Brown,Manmohan V Ranadive, Barbara A Schibly,George E Bettinger,Nandadeva Lokugamage,Lawrence Korman,John C Morrill,Clarence J Peters
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