基本信息
浏览量:671
职业迁徙
个人简介
Major Research Achievements
discovery of the most important characteristics of immunosenescence in humans;
proposal of the “remodelling” and “inflammaging” theories of aging, and of the conceptualization of the “liquid immune self” and “immunobiography”;
pioneering studies on immune response and stress throughout evolution;
pioneering studies on genetics, epigenetics, proteomics, metabolomics, metagenomics, glycomics of human aging and longevity (centenarians);
discovery of nuclear genes and mtDNA polymorphisms associated to human longevity, Alzheimer and T2D;
new biomarkers of aging (gut microbiome; N-glycans; DNA methylation; inflamma-miRs; metabolomic and lipidomic markers);
identification of immunological, epigenetic and glycomic biomarkers of the Down Syndrome as a model of accelerating aging;
mathematical modeling of the immune system and the proteasome.
discovery of the most important characteristics of immunosenescence in humans;
proposal of the “remodelling” and “inflammaging” theories of aging, and of the conceptualization of the “liquid immune self” and “immunobiography”;
pioneering studies on immune response and stress throughout evolution;
pioneering studies on genetics, epigenetics, proteomics, metabolomics, metagenomics, glycomics of human aging and longevity (centenarians);
discovery of nuclear genes and mtDNA polymorphisms associated to human longevity, Alzheimer and T2D;
new biomarkers of aging (gut microbiome; N-glycans; DNA methylation; inflamma-miRs; metabolomic and lipidomic markers);
identification of immunological, epigenetic and glycomic biomarkers of the Down Syndrome as a model of accelerating aging;
mathematical modeling of the immune system and the proteasome.
研究兴趣
论文共 1269 篇作者统计合作学者相似作者
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AGEING RESEARCH REVIEWS (2024): 102144-102144
Ageing Research Reviews (2024): 102253-102253
EBioMedicine (2023): 104692-104692
Cellsno. 6 (2023): 927-927
Ageing Research Reviews (2023): 101982-101982
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