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Dr. Shapiro directed research on computational and experimental RNA structure prediction and analysis and pioneered research in the emerging field of RNA nanobiology. His work led to several novel RNA folding and analysis algorithms, experimental techniques and discoveries in RNA biology. His interests included RNA nanobiology, nucleic acid structure prediction and analysis, the relationships between RNA structure and function. He fostered a synergy between computational and experimental techniques, where computationally designed novel RNA based nanostructures were shown to be able to self-assemble as predicted and be delivered to cell cultures and mouse models to control gene expression and thus show potential for use in RNA-based therapeutics.
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论文共 208 篇作者统计合作学者相似作者
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Molecules (Basel, Switzerland)no. 4 (2023): 1803-1803
RNA Nanotechnology and Therapeuticspp.121-124, (2022)
Anu Puri,Faisal Ibrahim,André O'Reilly Beringhs, Camryn Isemann,Paul Zakrevsky, Abigail Whittenburg,Derek Hargrove,Tapan Kanai, Rebecca S Dillard,Natalia de Val,Michael H Nantz,Xiuling Lu,
Regan M LeBlanc,Wojciech K Kasprzak,Andrew P Longhini,Lukasz T Olenginski,Fardokht Abulwerdi, Stefano Ginocchio, Brigit Shields, Julie Nyman, Maryia Svirydava,Claudia Del Vecchio,Joseph Ivanic,John S Schneekloth,
RNA Nanotechnology and Therapeuticspp.333-335, (2022)
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