Research Interests My main areas of interest are in two areas: thrombosis and vein graft complications. In the field of thrombosis and hemostasis, I have developed novel models for inducing thrombosis and for intravital fluorescence imaging of thrombus development. Recent applications of these models and evaluative measures have explored the roles of a number of thrombosis-associated factors in augmenting or inhibiting clot formation: tissue factor pathway inhibitor, polyphosphate, surface-exposed collagen, elevated prothrombin, and several standard and new anti-platelet agents and anticoagulants. Continuing studies are exploring related thrombus-modulating factors and novel approaches to preventing thrombosis.