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Over the past 12 years, I have run a successful lab at the Hospital for Sick Children/University of Toronto. However, I was recently recruited back to the US in the fall of 2021 to Oregon Health & Science University in the Department of Pediatric Neurooncology, with joint appointments at the Vollum Institute and the Knight Cancer Institute. This opportunity is a perfect fit because I was specifically recruited to continue our work on the biology of stemness and identification of normal stemness pathways that have gone awry in human brain tumors as well as our work on fundamental neuro- and glio-genesis using planarians. On the cancer side, my lab uses comparative genomics and functional screens to find new regulators of stemness that are also conserved in evolution and drive cancer stem cells. On the neurogenesis side, we are trying to identify the neural stem cells and pathways of neurogenesis in planarians during both homeostasis and regeneration. Together, we take unique approaches to long-standing unknowns in neural cancers and neurobiology.
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Cell Reportsno. 1 (2024): 113621-113621
Methods in molecular biology (Clifton, N.J.) (2023): 157-168
BMC biologyno. 1 (2023): 1-22
DEVELOPMENTno. 18 (2023)
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