We are interested in materials composed of well-defined polymers with selected functionality, composition, and molecular architecture. Particular focus is on water-soluble polymers that are stimuli-responsive. Such “smart” polymers have the ability to self-assemble or dissociate in solution in response to changes in their surroundings. Potential target applications include controlled and targeted drug delivery, surface modification, and self-healing materials. Our interests are at the interface of bio-, organic, nano-, and polymer chemistry, with particular focus on fusing the fields to prepare materials with synergistic properties.