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职业迁徙
个人简介
Funding awarded
REACH: Research Enterprise to Advance a Cure for HIV awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2021 - 2026
Understanding Immune Evasion by HIV-1 Repliclones awarded by Health Resources & Services Administration Principal Investigator Subaward 2021 - 2026
Characterization of a Memory CD4+ T-cell Humanized Mouse Model for the Evaluation of Autologous Cell Therapies and Studies of HIV Persistence awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2020 - 2022
Defining & Characterizing Novel Mechanisms by which HIV-infected Primary CD4+ T-cells Intrinsically Resist Elimination by CTL awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2020 - 2021
Integrating Transcriptomic and Proviral Integration Site Data-Sets to Define Mechanisms of ''CTL Resistance'' in Reservoir awarded by American Foundation for AIDS Research (amfAR) Principal Investigator 2020 - 2021
Deciphering Mechanisms of HIV Latency Reversal in Perinatal Infection awarded by United States Food & Drug Administration Principal Investigator Subaward 2020 - 2025
Targeting STAT SUMOylation for HIV cure strategies awarded by National Institute of Allergy & Infectious Diseases Principal Investigator Subaward 2020 - 2025
Biomaterials-Enhanced NK Cells for Improved Elimination of the HIV Reservoir awarded by National Institute of Allergy & Infectious Diseases Principal Investigator Subaward 2020 - 2023
Measurement of HIV Proviral Reservoir Using Intact Proviral DNA Assay Principal Investigator Subaward 2020 - 2021
Targeted delivery of cytopathicity enhancing agents, and co-ordination with shock and kill, to reduce HIV reservoirs Principal Investigator 2019 - 2024
Immunologic control of HIV-1 through combination bNAbs and biologics awarded by National Institute of Neurological Disorders & Stroke Principal Investigator Subaward 2019 - 2024
CTL-Mediated Elimination of Replication Competent vs. Defective HIV Proviruses from Natural Latent Reservoirs: Roles of Antigen Specificity and Functional Characteristics awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2018 - 2022
Engineered CTL with Inducible Ab Secretion; a Tripartite attack on HIV Reservoirs awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2018 - 2021
HIV induced anti-cancer HERV immunity in prostate, breast and colon cancers awarded by National Cancer Institute Co-Investigator 2018 - 2022
BELIEVE: Bench to Bed Enhanced Lymphocyte Infusions to Engineer Viral Eradication awarded by National Institute of Allergy & Infectious Diseases Co-Investigator 2018 - 2022
Comparison of Dendritic Cell-Based Therapeutic Vaccine Strategies for HIV Functional Cure awarded by National Institute of Allergy & Infectious Diseases Principal Investigator Subaward 2018 - 2022
selected publications
Corrigendum to: Suboptimal Biological Sampling as a Probable Cause of False-Negative COVID-19 Diagnostic Test Results. The Journal of infectious diseases. 2021
A participant-derived xenograft model of HIV enables long-term evaluation of autologous immunotherapies. The Journal of experimental medicine. 2021
Author Correction: HIV-1 diversity considerations in the application of the Intact Proviral DNA Assay (IPDA). Nature communications. 2021
Selective BCL-XL Antagonists Eliminate Infected Cells from a Primary Cell Model of HIV Latency but not from Ex Vivo Reservoirs. Journal of virology. 2021
HIV-specific T cell responses reflect substantive in vivo interactions with antigen despite long-term therapy. JCI insight. 2021
The Intact Non-Inducible Latent HIV-1 Reservoir is Established In an In Vitro Primary TCM Cell Model of Latency. Journal of virology. 2021
REACH: Research Enterprise to Advance a Cure for HIV awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2021 - 2026
Understanding Immune Evasion by HIV-1 Repliclones awarded by Health Resources & Services Administration Principal Investigator Subaward 2021 - 2026
Characterization of a Memory CD4+ T-cell Humanized Mouse Model for the Evaluation of Autologous Cell Therapies and Studies of HIV Persistence awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2020 - 2022
Defining & Characterizing Novel Mechanisms by which HIV-infected Primary CD4+ T-cells Intrinsically Resist Elimination by CTL awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2020 - 2021
Integrating Transcriptomic and Proviral Integration Site Data-Sets to Define Mechanisms of ''CTL Resistance'' in Reservoir awarded by American Foundation for AIDS Research (amfAR) Principal Investigator 2020 - 2021
Deciphering Mechanisms of HIV Latency Reversal in Perinatal Infection awarded by United States Food & Drug Administration Principal Investigator Subaward 2020 - 2025
Targeting STAT SUMOylation for HIV cure strategies awarded by National Institute of Allergy & Infectious Diseases Principal Investigator Subaward 2020 - 2025
Biomaterials-Enhanced NK Cells for Improved Elimination of the HIV Reservoir awarded by National Institute of Allergy & Infectious Diseases Principal Investigator Subaward 2020 - 2023
Measurement of HIV Proviral Reservoir Using Intact Proviral DNA Assay Principal Investigator Subaward 2020 - 2021
Targeted delivery of cytopathicity enhancing agents, and co-ordination with shock and kill, to reduce HIV reservoirs Principal Investigator 2019 - 2024
Immunologic control of HIV-1 through combination bNAbs and biologics awarded by National Institute of Neurological Disorders & Stroke Principal Investigator Subaward 2019 - 2024
CTL-Mediated Elimination of Replication Competent vs. Defective HIV Proviruses from Natural Latent Reservoirs: Roles of Antigen Specificity and Functional Characteristics awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2018 - 2022
Engineered CTL with Inducible Ab Secretion; a Tripartite attack on HIV Reservoirs awarded by National Institute of Allergy & Infectious Diseases Principal Investigator 2018 - 2021
HIV induced anti-cancer HERV immunity in prostate, breast and colon cancers awarded by National Cancer Institute Co-Investigator 2018 - 2022
BELIEVE: Bench to Bed Enhanced Lymphocyte Infusions to Engineer Viral Eradication awarded by National Institute of Allergy & Infectious Diseases Co-Investigator 2018 - 2022
Comparison of Dendritic Cell-Based Therapeutic Vaccine Strategies for HIV Functional Cure awarded by National Institute of Allergy & Infectious Diseases Principal Investigator Subaward 2018 - 2022
selected publications
Corrigendum to: Suboptimal Biological Sampling as a Probable Cause of False-Negative COVID-19 Diagnostic Test Results. The Journal of infectious diseases. 2021
A participant-derived xenograft model of HIV enables long-term evaluation of autologous immunotherapies. The Journal of experimental medicine. 2021
Author Correction: HIV-1 diversity considerations in the application of the Intact Proviral DNA Assay (IPDA). Nature communications. 2021
Selective BCL-XL Antagonists Eliminate Infected Cells from a Primary Cell Model of HIV Latency but not from Ex Vivo Reservoirs. Journal of virology. 2021
HIV-specific T cell responses reflect substantive in vivo interactions with antigen despite long-term therapy. JCI insight. 2021
The Intact Non-Inducible Latent HIV-1 Reservoir is Established In an In Vitro Primary TCM Cell Model of Latency. Journal of virology. 2021
研究兴趣
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biorxiv(2023)
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Research Square (Research Square) (2023)
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