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个人简介
I have used honeybees, leaf cutting ants and bumblebees to study aspects of social insect reproduction and immunity. To do this I pursue an integrative approach, which combines biochemical technologies such as proteomics and evolutionary biology. An important part of my work is to conduct biochemical analyses and to use their outcomes to formulate hypotheses that can be experimentally tested in the field. My idea is to help building a new field of research, which I refer to as evolutionary proteomics. Evolutionary proteomics will not only aim to understand evolutionary processes at the protein level, but will also attempt to quantify variations in proteomic profiles and investigate their consequences for natural and sexual selection. I am specifically interested in the proteomic mechanisms underlying self-non-self recognition systems in honeybees and leaf-cutting ants, and will continue to address how transcriptional and translational modifications translate into protein-level mechanisms for discrimination against non-self agents such as microbial and protozoan parasites or ejaculates of competing males during insemination. Such knowledge will be of fundamental significance, but will also be applied in new breeding programs for honeybee stock improvement in collaboration with beekeepers in California and Western Australia. My overall goal is to develop a scientifically-guided breeding program that selects for honeybee lineages that are tolerant against diseases and more versatile in coping with environmental stressors. The species I use for my work are all ideal model species for such work as they can be kept in the lab and the availability of techniques such as artificial insemination allow sophisticated experimental manipulations.
研究兴趣
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Journal of economic entomology (2024)
CoRR (2024)
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Bee Worldpp.1-4, (2023)
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Molecular & cellular proteomics : MCPno. 8 (2022): 100257-100257
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