基本信息
浏览量:2
职业迁徙
个人简介
Dr. Ky’s research interests center on translational cardiovascular epidemiology and focus particularly on novel signaling pathways and mechanisms in human heart failure, cardiac remodeling, and cancer therapy cardiotoxicity.
Her current research is concentrated in three areas. First, her work on neuregulin signaling asks, how does circulating neuregulin relate to human heart failure and cardiac remodeling? She is the principal investigator of a longitudinal study to determine the association between circulating neuregulin levels and cardiac remodeling and clinical outcomes in the Penn Heart Failure Study(link is external) and the Chronic Renal Insufficiency Cohort(link is external).
Second, her work on studies in mechanistic biomarkers in cancer therapy cardiotoxicity seeks to define novel circulating biomarkers and genetic variations predictive of cancer therapy cardiotoxicity. The team’s objective is to gain mechanistic and translational insight into the pathophysiology of this disease. Ongoing studies look at specific pathways and biomarkers of interest and at proteomics discovery across various cardiotoxic regimens.
Finally, Dr. Ky’s work on myocardial mechanics in cancer therapy cardiotoxicity and heart failure seeks to gain insight into alterations in myocardial mechanics and sensitive measures of cardiac function, as defined by echocardiography, in patients exposed to cardiotoxic chemotherapy regimens and in patients with chronic heart failure.
Her current research is concentrated in three areas. First, her work on neuregulin signaling asks, how does circulating neuregulin relate to human heart failure and cardiac remodeling? She is the principal investigator of a longitudinal study to determine the association between circulating neuregulin levels and cardiac remodeling and clinical outcomes in the Penn Heart Failure Study(link is external) and the Chronic Renal Insufficiency Cohort(link is external).
Second, her work on studies in mechanistic biomarkers in cancer therapy cardiotoxicity seeks to define novel circulating biomarkers and genetic variations predictive of cancer therapy cardiotoxicity. The team’s objective is to gain mechanistic and translational insight into the pathophysiology of this disease. Ongoing studies look at specific pathways and biomarkers of interest and at proteomics discovery across various cardiotoxic regimens.
Finally, Dr. Ky’s work on myocardial mechanics in cancer therapy cardiotoxicity and heart failure seeks to gain insight into alterations in myocardial mechanics and sensitive measures of cardiac function, as defined by echocardiography, in patients exposed to cardiotoxic chemotherapy regimens and in patients with chronic heart failure.
研究兴趣
论文共 313 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Ravi B. Patel,Frank E. Silvestry,Jan Komtebedde, Scott D. Solomon,Gerd Hasenfuß,Sheldon E. Litwin,Barry A. Borlaug,Matthew J. Price, Rami Kawash,Scott L. Hummel,Donald E. Cutlip,Martin B. Leon,
JAMA Cardiology (2024)
Jenica N. Upshaw,Jason Nelson, Benjamin Sweigart,Angie Mae Rodday,Anita J. Kumar,Marvin A. Konstam,John B. Wong,Bonnie Ky, Samuel Karmiy,Jonathan W. Friedberg,Andrew M. Evens,David M. Kent,
JACC: CardioOncologyno. 2 (2024): 200-213
Ravi B Patel,Frank E Silvestry,Jan Komtebedde, Scott D Solomon,Gerd Hasenfuß,Sheldon E Litwin,Barry A Borlaug,Matthew J Price, Rami Kawash,Scott L Hummel,Donald E Cutlip,Martin B Leon,
JAMA cardiology (2024)
Cardio-Oncology Practice Manual : a Companion to Braunwald 's Heart Diseasepp.205-218, (2023)
Moriah P. Bellissimo,Justin M. Canada,Jennifer H. Jordan,Amy C. Ladd,Kerryn W. Reding, Tonya L. Moore,William O. Ntim,Emily M. Heiston,Peter Brubaker,Shannon L. Mihalko,Ralph D'Agostino Jr, Nate O'Connell,
JACC: CardioOncologyno. 5 (2023): 641-652
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORKno. 10 (2023): 1039-+
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn