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We are a discovery-driven research group working at the interface between statistical physics, developmental biology, and bioengineering. We combine quantitative organism-wide fluorescence imaging ("deep imaging"), functional genomics ("deep sequencing"), and statistical modeling to study systems biology and evolutionary cell biology of flatworms, including free living planarians and parasitic flukes. Using these animals, we seek to understand quantitatively the fundamental rules that control stem cell collective behavior to optimize tissue regeneration, remolding, and adaptation.
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Richard Nelson Hall,Hongquan Li,Chew Chai, Sidney Vermeulen, Robin Rio, Eun Sun Song, Jesse Gibson,Manu Prakash,Andrew Z Fire,Bo Wang
crossref(2024)
Methods in molecular biology (Clifton, N.J.) (2023): 263-275
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biorxiv(2023)
CELLno. 17 (2023): 3606-3618.e16
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
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