Bjorn C. Knollmann

Professor

Oates Institute for Experimental Therapeutics;Division of Clinical Pharmacology Department of Medicine and Pharmacology, Vanderbilt University Medical Center;Vanderbilt Center for Arrhythmia Research and Therapeutics, Vanderbilt University Medical Center;E-C coupling and Arrhythmia Lab, Vanderbilt University Medical Center

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基本信息

Career Trajectory

Bio

His primary interest is finding new mechanisms and treatments for heart rhythm disorders. His laboratory and clinical research programs are supported by National Institute of Health (NIH) R01 and American Heart Association (AHA) grants. Work in his laboratory investigates molecular arrhythmia mechanisms involving alterations in the functioning of myofilaments and calcium release channels. In addition, the lab is developing and testing new anti-arrhythmic therapies in animal models and in humans.

Research Interests

Papers共 432 篇Author StatisticsCo-AuthorSimilar Experts

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A High-Performance Extracellular Field Potential Analyzer for Ipsc-Derived Cardiomyocytes

Nidhi Patel, Alex Shen,Yuko Wada,Marcia Blair,Devyn Mitchell,Loren Vanags, Suah Woo, Matthew Ku, Kundivy Dauda, William Morris, Minjoo Yang,Björn C Knollmann,Joe-Elie Salem,Andrew M Glazer,Brett M Kroncke

Scientific reportsno. 1 (2025): 8948-8948

Cited0Views0WOSNATUREBibtex

Structural Evaluation of RYR2 -CPVT Missense Variants and Continuous Bayesian Estimates of Their Penetrance

Kohei Yamauchi, Matthew Ku, Devyn W Mitchell, Alex Shen, Kundivy Dauda,Loren Vanags,Jeffrey Schmeckpeper,Bjorn C Knollmann, Matthew J O'Neill,Brett M Kroncke

medRxiv the preprint server for health sciences (2025)

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Translationally Controlled Tumor Protein Interacts with Connexin 43 and Facilitates Intercellular Coupling Between Cardiomyocytes

Yaopeng Hu,Wenqian Cai,Yuko Hidaka, Keizo Hiraishi, Jiehui Cang,Masanari Umemura,Utako Yokoyama,Björn C Knollmann,Yoshihiro Ishikawa,Takayuki Fujita

Frontiers in cell and developmental biology (2025): 1549063-1549063

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Increased L-type Calcium Current Causes Action Potential Prolongation in Jervell and Lange-Nielsen Syndrome and is a Drug Target

Yuko Wada, Marcia A Blair, Teresa L Strickland, Julie A Laudeman, Kyungsoo Kim, M Lorena Harvey,Joseph F Solus, Darlene F Fountain,Bjorn C Knollmann,M Benjamin Shoemaker,Prince J Kannankeril,Dan M Roden

medRxiv the preprint server for health sciences (2025)

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Pharmacological Enhancement of Small Conductance Ca2+-Activated K+ Channels Suppresses Cardiac Arrhythmias in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia

Roland Veress,Radmila Terentyeva,Andriy E Belevych,Fruzsina Perger,Zuzana Nichtova, Anastasia Pokrass, Yujia Cheng, Snizhana Chorna,Isabelle Deschenes,Sandor Gyorke,Bjorn Knollmann,Richard T Clements,Harpreet Singh,Bin Liu,Gyorgy Csordas,Shanna Hamilton,Dmitry Terentyev

Circulation research (2025)

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Hypertrophic Cardiomyopathy Dysfunction Mimicked in Human Engineered Heart Tissue and Improved by Sodium-Glucose Cotransporter 2 Inhibitors

Paul J. M. Wijnker,Rafeeh Dinani, Nico C. van der Laan,Sila Algul,Bjorn C. Knollmann,Arie O. Verkerk,Carol Ann Remme,Coert J. Zuurbier,Diederik W. D. Kuster,Jolanda van der Velden

CARDIOVASCULAR RESEARCHno. 3 (2024): 301-317

Cited6Views0WOSBibtex

The Backbone Constitution Drives Passive Permeability Independent of Side Chains in Depsipeptide and Peptide Macrocycles Inspired by Ent-Verticilide

Madelaine P. Thorpe,Abigail N. Smith,Daniel J. Blackwell,Corey R. Hopkins,Bjorn C. Knollmann,Wendell S. Akers,Jeffrey N. Johnston

CHEMICAL SCIENCEno. 36 (2024): 14977-14987

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Deciphering the Molecular Code Underlining Postnatal Cardiomyocyte Maturation by an RNA Splicing Factor RBFox1

Jijun Huang, Josh Lee,Christoph Rau,Arash Pezhouman,Tomohiro Yokota,Hiromi Miwa, Matthew Feldman, Tsz Kin Kong,Ziyue Yang, Woan Ting Tay,Ivan Pushkarsky,Kyungsoo Kim,Shan Parikh,Shreya Udani,Boon Seng Soh,Chen Gao,Linsey Stiles,Orian Shirihai,Bjorn Knollmann,Reza Ardehali,Dino Di Carlo, Dale Abel,Yibin Wang

CIRCULATION RESEARCH (2024)

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The Proteostasis Interactomes of Trafficking-Deficient Variants of the Voltage-Gated Potassium Channel KV11.1 Associated with Long QT Syndrome

Christian L. Egly, Lea A. Barny,Tri Do,Eli F. Mcdonald,Bjorn C. Knollmann,Lars Plate

JOURNAL OF BIOLOGICAL CHEMISTRYno. 7 (2024)

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The Proteostasis Interactomes of Trafficking-Deficient KV11.1 Variants Associated with Long QT Syndrome and Pharmacological Chaperone Rescue

Christian L Egly, Lea Barny,Tri Do,Eli F McDonald,Lars Plate,Bjorn C Knollmann

bioRxiv the preprint server for biology (2024)

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Author Statistics

#Papers: 432

#Citation: 10648

H-Index: 52

G-Index: 94

Sociability: 7

Diversity: 3

Activity: 38

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