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个人简介
I study megakaryocytes - large, rare cells found in the bone marrow that release blood platelets into the circulation and also produce many growth factors and other proteins that regulate blood cell development and the bone marrow microenvironment. My group applies state-of-the-art single-cell approaches to clarify the cellular pathways by which megakaryocytes arise from haematopoietic stem cells. This is important as in certain malignancies, such as erythro-megakaryocytic leukaemias and myeloproliferative neoplasms, megakaryocytes develop abnormally and contribute to key pathological features of the disease, including the harmful scarring that destroys the bone marrow.
研究兴趣
论文共 133 篇作者统计合作学者相似作者
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Antonio Rodriguez-Romera,Bethan Psaila
The Hematologistno. 3 (2024)
Aude-Anais Olijnik, Antonio Rodriguez-Romera, Zoë C. Wong, Yuqi Shen,Jasmeet S. Reyat,Natalie J. Jooss,Julie Rayes,Bethan Psaila,Abdullah O. Khan
Nature Protocolspp.1-30, (2024)
Donal P. McLornan,Anna L. Godfrey,Anna Green, Rebecca Frewin,Siamak Arami,Jessica Brady, Nauman M. Butt,Catherine Cargo,Joanne Ewing,Sebastian Francis,Mamta Garg,Claire Harrison,
Alex Rampotas,Luke Carter-Brzezinski,Tim C. P. Somervaille, James Forryan, Fotios Panitsas,Claire Harrison,Ruth Witherall,Andrew J. Innes,Louise Wallis,Naumann M. Butt,Bethan Psaila,Adam J. Mead,
Donal P. McLornan,Bethan Psaila,Joanne Ewing,Andrew Innes,Siamak Arami,Jessica Brady, Nauman M. Butt,Catherine Cargo,Nicholas C. P. Cross,Sebastian Francis, Rebecca Frewin,Mamta Garg,
BRITISH JOURNAL OF HAEMATOLOGYno. 1 (2024): 136-150
Zenodo (CERN European Organization for Nuclear Research)no. 9 (2023): 1531-1541
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Jennifer O Sullivan, Sean Wen, Affaf Aliouat,Alba Rodriguez-Meira,Sally-Ann Clark, Neil Ashley, Amy Wood, Ramy Slama,Guanlin Wang,Angela Hamblin,Lauren Murphy,Christina Simoglou Karali,
Blood (2023): 861
Nikolaos Sousos,Lauren Murphy, Sean Wen,Angela Hamblin,Sally-Ann Clark,Christina Simoglou Karali, Jessica Whittle,Zemin Ren,Haseeb Rahman, Nawshad Hayder, Akriti Rastogi, Michael Jacobs,
BLOOD (2023)
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