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Publications:
1. Synthesis of novel, potent, diol-based HIV-1 protease inhibitors via intermolecular pinacol homocoupling of (2S)-2-benzyloxymethyl-4-phenylbutanal. Muhlman A, Lindberg J, Classon B, Unge T, Hallberg A, Samuelsson B. J Med Chem 2001, 44(21), 3407-16.
2. Novel morpholinone-based D-Phe-Pro-Arg mimics as potential thrombin inhibitors: design, synthesis, and X-ray crystal structure of an enzyme inhibitor complex. Dahlgren A, Johansson PO, Kvarnstrom I, Musil D, Nilsson I, Samuelsson B. Bioorg Med Chem 2002, 10(6), 1829-39.
3. Solid-phase library synthesis of reversed-statine type inhibitors of the malarial aspartyl proteases plasmepsin I and II. Dahlgren A, Kvarnstrom I, Vrang L, Hamelink E, Hallberg A, Rosenquist A, Samuelsson B. Bioorg Med Chem. 2003, 11(6), 827-41.
4. Synthesis of novel thrombin inhibitors. Use of ring-closing metathesis reactions for synthesis of P2 cyclopentene- and cyclohexenedicarboxylic acid derivatives. Thorstensson F, Kvarnstrom I, Musil D, Nilsson I, Samuelsson B. J Med Chem. 2003, 46(7), 1165-79.
5. Design and Synthesis of Potent Inhibitors of the Malaria Aspartyl Proteases Plasmepsin I and II. Use of Solid-Phase Synthesis to Explore Novel Statine Motifs. Johansson, Per-Ola; Chen, Yantao; Belfrage, Anna Karin; Blackman, Michael J.; Kvarnström, Ingemar; Jansson, Katarina; Vrang, Lotta; Hamelink, Elizabeth; Hallberg, Anders; Rosenquist, Asa; Samuelsson, Bertil. Journal of Medicinal Chemistry (2004), 47(13), 3353-3366.
6. Design and Synthesis of Potent Inhibitors of Plasmepsin I and II: X-ray Crystal Structure of Inhibitor in Complex with Plasmepsin II.
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