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Identification and de novo structure elucidation of natural products with ecological implications from natural sources is a major task of Bernd Schneider’s research group. Modern NMR methods are implemented into NMR-based plant metabolic profiling and metabolomics studies. For example, phenylphenalenone-producing plant families were recently studied in-depth in his group and numerous plant metabolic studies have been performed together with collaborators. Products of isolated or recombinant enzymes are another important subject for NMR-spectroscopic analysis. NMR spectrometers (700 and 500 MHz) equipped with cryogenically cooled probes are available for measuring mass-limited samples. LC-DAD-MS-NMR coupling is especially useful to identify natural products without isolation.
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TETRAHEDRON LETTERS (2024): 154907
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