基本信息
浏览量:5
职业迁徙
个人简介
Research interests
Our research examines the structure and function of a family of pore forming proteins known as ion channels. We aim to understand the mechanisms by which these proteins can identify and transport molecules across the cell membrane, and how the pores open and close to control this transport. In addition we are interested in studying transport in other kinds of pores, be they in proteins, crystaline materials or synthetic membranes. Gaining a fundamental understanding of the operation of biological pores has allowed us to design synthetic porous membranes that can be used for the desalination of sea water or to remove dangerous contaminants from water supplies.
Proteins and macromolecules can be difficult to study due to their size, functioning at the interface of microscopic molecular behaviour and macroscopic mechanical behaviour. To investigate them we use a combination of computational techniques including quantum calculations, molecular dynamics, and macroscopic modelling. In addition we utilise FRET microscopy (Förster Resonance Energy Transfer) to experimentally study the conformational changes of proteins as they function.
Awards
Replacing Animals in Medical Research Grant, 2021
Vice Chancellor's Award for Excellence in Education, for Outstanding Contribution to Student Learning, 2020
Professional staff & Excellence in Education award, 2019
ARC Future Fellowship, 2013
Eureka Prize Finalist, 2011
Young Tall Poppy Science Award, 2011
Young Scientist of the Year (WA), 2005
Young Biophysicist Award, 2005
Our research examines the structure and function of a family of pore forming proteins known as ion channels. We aim to understand the mechanisms by which these proteins can identify and transport molecules across the cell membrane, and how the pores open and close to control this transport. In addition we are interested in studying transport in other kinds of pores, be they in proteins, crystaline materials or synthetic membranes. Gaining a fundamental understanding of the operation of biological pores has allowed us to design synthetic porous membranes that can be used for the desalination of sea water or to remove dangerous contaminants from water supplies.
Proteins and macromolecules can be difficult to study due to their size, functioning at the interface of microscopic molecular behaviour and macroscopic mechanical behaviour. To investigate them we use a combination of computational techniques including quantum calculations, molecular dynamics, and macroscopic modelling. In addition we utilise FRET microscopy (Förster Resonance Energy Transfer) to experimentally study the conformational changes of proteins as they function.
Awards
Replacing Animals in Medical Research Grant, 2021
Vice Chancellor's Award for Excellence in Education, for Outstanding Contribution to Student Learning, 2020
Professional staff & Excellence in Education award, 2019
ARC Future Fellowship, 2013
Eureka Prize Finalist, 2011
Young Tall Poppy Science Award, 2011
Young Scientist of the Year (WA), 2005
Young Biophysicist Award, 2005
研究兴趣
论文共 175 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
bioRxiv (Cold Spring Harbor Laboratory) (2024)
ELIFE (2024)
Yaoyao Han,Zijing Zhou,Ruitao Jin,Fei Dai,Yifan Ge, Xisan Ju, Xiaonuo Ma,Sitong He,Ling Yuan,Yingying Wang,Wei Yang,Xiaomin Yue,
Naturepp.1-9, (2024)
Biophysics and physicobiologyno. 4 (2023): n/a-n/a
Biopolymersno. 7 (2023)
引用0浏览0引用
0
0
Geza Berecki,Elaine Tao,Katherine B Howell,Rohini K Coorg, Kris Kahlig, Markus Wolff,Ben Corry,Steven Petrou
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Desalination (2023): 116659-116659
引用0浏览0引用
0
0
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn