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Kobilka is best known for his research on the structure and activity of G protein-coupled receptors (GPCRs); in particular, work from Kobilka's laboratory determined the molecular structure of the β2-adrenergic receptor. This work has been highly cited by other scientists because GPCRs are important targets for pharmaceutical therapeutics, but notoriously difficult to work with in X-ray crystallography. Before, rhodopsin was the only G-protein coupled receptor where the structure had been determined at high resolution. The β2-adrenergic receptor structure was soon followed by the determination of the molecular structure of several other G-protein coupled receptors.
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Naturepp.1-6, (2024)
Marina Casiraghi,Haoqing Wang, Patrick Brennan, Chris Habrian,Harald Hübner, Maximilian F. Schmidt, Luis Maul,Biswaranjan Pani, Sherif M.F.M. Bahriz, Bing Xu, Elizabeth White,Roger K. Sunahara,
biorxiv(2024)
Marina Casiraghi,Haoqing Wang, Patrick Brennan,Chris Habrian,Harald Hubner,Maximilian F Schmidt, Luis Maul,Biswaranjan Pani, Sherif MFM Bahriz,Bing Xu, Elizabeth White,Roger K Sunahara,
crossref(2024)
Jiawei Zhao,Matthias Elgeti, Evan S O'Brien,Cecília P Sár, Amal Ei Daibani,Jie Heng,Xiaoou Sun, Elizabeth White,Tao Che,Wayne L Hubbell,Brian K Kobilka,Chunlai Chen
Makaía M. Papasergi-Scott,Guillermo Pérez-Hernández, Hossein Batebi,Yang Gao, Gözde Eskici,Alpay B. Seven, Ouliana Panova, Daniel Hilger,Marina Casiraghi, Feng He,Luis Maul, Peter Gmeiner,
Naturepp.1-10, (2024)
Marina Casiraghi,Haoqing Wang, Patrick Brennan,Chris Habrian,Harald Hübner,Maximilian F Schmidt, Luis Maul,Biswaranjan Pani, Sherif M F M Bahriz,Bing Xu, Elizabeth White,Roger K Sunahara,
bioRxiv : the preprint server for biology (2024)
NATURE COMMUNICATIONSno. 1 (2023)
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NATURE COMMUNICATIONSno. 1 (2023)
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