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In earlier studies with colleagues Michael Wigler and Saul Silverstein, gene transfer techniques were developed that permit the introduction of virtually any gene into any cell. These studies not only allowed for a novel approach to isolate genes but also provided a detailed analysis of how they worked. At the same time, these experiments allowed for the production of an increasingly large number of clinically important proteins. These studies also led to the isolation and functional analysis of a gene for the lymphocyte surface protein, CD4, the cellular receptor for the AIDS virus, HIV.
I then began to apply molecular biology to problems in neuroscience with the expectation that genetics could interface with neuroscience to approach the tenuous relationship between genes, behavior, and perception. My studies on the logic of the sense of smell revealed over a thousand genes involved in the recognition of odors and provided insight into how genes shape our perception of the sensory environment. My current work centers on how the recognition of odors is translated into an internal representation of sensory quality in the brain and how this representation leads to meaningful thoughts and behavior.
I then began to apply molecular biology to problems in neuroscience with the expectation that genetics could interface with neuroscience to approach the tenuous relationship between genes, behavior, and perception. My studies on the logic of the sense of smell revealed over a thousand genes involved in the recognition of odors and provided insight into how genes shape our perception of the sensory environment. My current work centers on how the recognition of odors is translated into an internal representation of sensory quality in the brain and how this representation leads to meaningful thoughts and behavior.
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论文共 239 篇作者统计合作学者相似作者
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Moise Bonheur, Kurtis J. Swartz,Melissa G. Metcalf,Anna Zhukovskaya,Avirut Mehta, Kristin E. Connors, Julia Barasch,Xinke Wen,Andrew Jamieson,Kelsey C. Martin,Richard Axel,Daisuke Hattori
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Jennifer J. Bussell, Ryan P. Badman,Christian D. Márton,Ethan S. Bromberg-Martin,L.F. Abbott,Kanaka Rajan,Richard Axel
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Tessa Montague, Daniella Garcia-Rosales, Connor Gibbons, Thomas Barlow, Adriana Nemes, Mycah Simmons, Erica Shook,Larry Abbott,Richard Axel
TRANSGENIC RESEARCHno. SUPSUPPL 1 (2023): S315-S315
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Ryan Lorig-Roach, Melissa Meredith,Jean Monlong,Miten Jain,Hugh Olsen,Brandy McNulty,David Porubsky,Tessa Montague,Julian Lucas, Chris Condon,Jordan Eizenga,Sissel Juul,
biorxiv(2023)
Nature Neuroscienceno. 6 (2023): 1054-1067
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Tessa G. Montague, Isabelle J. Rieth, Sabrina Gjerswold-Selleck, Daniella Garcia-Rosales, Sukanya Aneja, Dana Elkis, Nanyan Zhu, Sabrina Kentis, Frederick A. Rubino, Adriana Nemes, Katherine Wang, Luke A. Hammond,
Moise Bonheur, Kurtis J. Swartz,Melissa G. Metcalf,Xinke Wen,Anna Zhukovskaya,Avirut Mehta, Kristin E. Connors, Julia G. Barasch,Andrew R. Jamieson,Kelsey C. Martin,Richard Axel,Daisuke Hattori
Nature Neuroscienceno. 7 (2023): 1295-1307
Tessa G. Montague,Isabelle J. Rieth, Sabrina Gjerswold-Selleck, Daniella Garcia-Rosales, Sukanya Aneja, Dana Elkis,Nanyan Zhu, Sabrina Kentis,Frederick A. Rubino, Adriana Nemes,Katherine Wang,Luke A. Hammond,
bioRxiv (Cold Spring Harbor Laboratory) (2022)
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