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Mechanisms of host disease resistance in apples; particularly to fire blight and apple scab
Quantitative genetics, genomics, genetic diversity, and pre-breeding
Rapid disease detection, pathogen identification, and high-throughput phenotyping tools
Recent Research
My research focus is to characterize mechanisms of disease resistance and pathogenesis, strategies and tools for accelerated and targeted improvement of disease resistance in rosaceous fruits, primarily apples, and to develop high-throughput methods for plant resistance phenotyping. We use quantitative genetics, QTL and association mapping, genomics, transcriptomics and bioinformatics to detect genetic regions and candidate genes controlling resistance and susceptibility to fungal and bacterial diseases of apples such as fire blight and apple scab. We also identify molecular markers tightly linked with QTLs and develop multiplexed marker assays to deploy multiple resistance alleles in commercially favored backgrounds through marker-assisted selection. Significant efforts are devoted into fine mapping and genome editing for gene discovery, validation and to develop pre-breeding lines with improved disease resistance. One of our reA number of fungal and bacterial diseases cause huge economic losses to the apple industry globally and are a threat to sustainable orchard production. To make research relevant to the apple industry and growers, our extension focus is on connecting lab and field research to the orchards for direct relevance and faster uptake of outputs. Either through extension specialists or direct connections with growers, we organize regular lab and orchard visits and participate in winter fruit schools, and field days. The aim of extension program is to get a strong understanding of concerns, needs, and interests of stakeholders, in order to orient and develop disease resistance research to address their priorities by applying modern genetics and genomic tools.search interests is to develop high-throughput resistance phenotyping methods to visualize, quantify and assess the severity of disease, and differences in response between plants in terms of symptoms and progress rate. For example, we are developing real-time imaging and analytical methods to monitor progress of fire blight infection, with concurrent sampling of transcripts and the metabolome to identify specific spatio-temporal mechanisms at genetic, cellular, and molecular levels. We also have interest in characterizing genetic diversity and virulence of Erwinia amylovora and Venturia inaequalis causal pathogens of fire blight and apple scab, respectively.
Mechanisms of host disease resistance in apples; particularly to fire blight and apple scab
Quantitative genetics, genomics, genetic diversity, and pre-breeding
Rapid disease detection, pathogen identification, and high-throughput phenotyping tools
Recent Research
My research focus is to characterize mechanisms of disease resistance and pathogenesis, strategies and tools for accelerated and targeted improvement of disease resistance in rosaceous fruits, primarily apples, and to develop high-throughput methods for plant resistance phenotyping. We use quantitative genetics, QTL and association mapping, genomics, transcriptomics and bioinformatics to detect genetic regions and candidate genes controlling resistance and susceptibility to fungal and bacterial diseases of apples such as fire blight and apple scab. We also identify molecular markers tightly linked with QTLs and develop multiplexed marker assays to deploy multiple resistance alleles in commercially favored backgrounds through marker-assisted selection. Significant efforts are devoted into fine mapping and genome editing for gene discovery, validation and to develop pre-breeding lines with improved disease resistance. One of our reA number of fungal and bacterial diseases cause huge economic losses to the apple industry globally and are a threat to sustainable orchard production. To make research relevant to the apple industry and growers, our extension focus is on connecting lab and field research to the orchards for direct relevance and faster uptake of outputs. Either through extension specialists or direct connections with growers, we organize regular lab and orchard visits and participate in winter fruit schools, and field days. The aim of extension program is to get a strong understanding of concerns, needs, and interests of stakeholders, in order to orient and develop disease resistance research to address their priorities by applying modern genetics and genomic tools.search interests is to develop high-throughput resistance phenotyping methods to visualize, quantify and assess the severity of disease, and differences in response between plants in terms of symptoms and progress rate. For example, we are developing real-time imaging and analytical methods to monitor progress of fire blight infection, with concurrent sampling of transcripts and the metabolome to identify specific spatio-temporal mechanisms at genetic, cellular, and molecular levels. We also have interest in characterizing genetic diversity and virulence of Erwinia amylovora and Venturia inaequalis causal pathogens of fire blight and apple scab, respectively.
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European Journal of Plant Pathologyno. 2 (2024): 249-259
JOURNAL OF AGRONOMY AND CROP SCIENCE (2023)
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PHYTOPATHOLOGYno. 12 (2023): 2174-2186
Alicia Serrano,Anna Wunsch,Jean Sabety, Janet van Zoeren, Michael Basedow,Mario Miranda Sazo,Marc Fuchs,Awais Khan
PLANTS-BASELno. 14 (2023): 2644-2644
Journal of Crop Science and Biotechnologyno. 1 (2023): 1-13
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