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个人简介
Research Abstract
TRAIL, a recently discovered member of the TNF superfamily of cytokines, may be a useful apoptotic-inducing treatment for prostate cancer. However, better understanding the molecular pathways that render a cell TRAIL-sensitive (PC3 and DU145 cells) vs. TRAIL-resistant (LNCaP cells) is crucial in order to selectively offer TRAIL to patients who would maximally benefit from the drug. The focus of my lab is to delineate the molecular mechanisms between TRAIL-resistant and TRAIL-sensitive prostate cancer cells.
Clinical Interests
Prostate cancer
Kidney cancer
Bladder cancer
Testicular, penile and genitourinary cancers
Laparoscopic surgery, Robotic surgery, Open surgery
Minimally invasive laser surgery for enlarged prostates
Brachytherapy (radioactive seeds) for prostate cancer
Board Certifications
American Board of Urology
Clinical Titles
Chief, Division of Urology
TRAIL, a recently discovered member of the TNF superfamily of cytokines, may be a useful apoptotic-inducing treatment for prostate cancer. However, better understanding the molecular pathways that render a cell TRAIL-sensitive (PC3 and DU145 cells) vs. TRAIL-resistant (LNCaP cells) is crucial in order to selectively offer TRAIL to patients who would maximally benefit from the drug. The focus of my lab is to delineate the molecular mechanisms between TRAIL-resistant and TRAIL-sensitive prostate cancer cells.
Clinical Interests
Prostate cancer
Kidney cancer
Bladder cancer
Testicular, penile and genitourinary cancers
Laparoscopic surgery, Robotic surgery, Open surgery
Minimally invasive laser surgery for enlarged prostates
Brachytherapy (radioactive seeds) for prostate cancer
Board Certifications
American Board of Urology
Clinical Titles
Chief, Division of Urology
研究兴趣
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FASEB journal : official publication of the Federation of American Societies for Experimental Biologyno. 2 (2024): e23416-e23416
Abigail J. Escobar,Suprita Krishna,K. Mikayla Flowers,Alejandro Abello,Boris Gershman,Andrew A. Wagner,Peter Chang,Ruslan Korets, Christopher J. Mistretta,Kristen L. Schreiber,Aria F. Olumi,Heidi J. Rayala
Journal of Urologyno. 2 (2024): 214-222
Ra'ad Al-Faouri,Christina Sharkey, Haeun Lee,Heidi Rayala, Ruslan Korets, Wei Wang,Zongwei Wang,Mukesh G. Harisinghani,Leo L. Tsai,Aria F. Olumi
The Journal of pathology (2024)
PLOS ONEno. 12 (2023)
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