Department of Medical Biotechnology University of Siena;Department of Pathology & Oncology, University of Siena;Sbarro Institute for Cancer Research & Molecular Medicine, Center of Biotechnology, College of Science & Technology, Temple University;Sbarro Health Research Organization
In his research throughout the years, Dr. Antonio Giordano identified a tumor suppressor gene, Rb2/p130, that has been found to be active in the lung, endometrial, brain, breast, liver, and ovarian cancers. Dr. Antonio Giordano also found that if doses of gamma radiation are combined with this gene, it accelerates the death of tumor cells. Dr. Antonio Giordano went on to discover Cyclin A, Cdk9, and Cdk10. Cdk9 is known to play critical roles in HIV transcriptions, the inception of tumors, and cell differentiation. They also play a part in muscle differentiation and have been linked to various genetic muscular disorders. Dr. Antonio Giordano has also developed patented technologies for diagnosing cancer.
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