Current Research
My main research focus is the exploration of the hypothesis that a novel classification of breast cancer based on phenotypic and molecular genetic characteristics will provide a more robust system for classification and therapeutic decision-making. As a consequence modern classification of breast cancer should be based on combined morphological, phenotypic (protein expression) and molecular genetic characteristics. This will provide a more robust system for classification and therapeutic decision-making and allow identification of novel therapeutic targets.

Breast cancer is a heterogenous disease comprising different molecular characteristics, clinical behaviour and treatment response. Luminal breast cancer comprise the majority of tumours but many patients relapse or develop resistance to current treatments particularly the more aggressive Luminal B tumours.