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Teaching Summary
Lecturing advanced immunology to MSc Oncology and MSc Cancer Immunology & Biotechnology students.
Our recent focus has concerned targeting specific intracellular signaling pathways in dendritic cells (DC) to modify their function or restore immuno-suppression resulting from malignancy. Key areas of interest include ATM-kinase, p38-MAPK, MEK-ERK and the Unfolded Protein Response pathway (UPR). We have shown that modulation of these pathways impacts on the generation of CD4-responses and this work is now in a pre-clinical phase. The importance of circulating DC including CD1c+ myeloid and SlanDC (collaboration with Dr. Marc Schmitz, Dresden) in advanced cancer patients is a major focus.
Lecturing advanced immunology to MSc Oncology and MSc Cancer Immunology & Biotechnology students.
Our recent focus has concerned targeting specific intracellular signaling pathways in dendritic cells (DC) to modify their function or restore immuno-suppression resulting from malignancy. Key areas of interest include ATM-kinase, p38-MAPK, MEK-ERK and the Unfolded Protein Response pathway (UPR). We have shown that modulation of these pathways impacts on the generation of CD4-responses and this work is now in a pre-clinical phase. The importance of circulating DC including CD1c+ myeloid and SlanDC (collaboration with Dr. Marc Schmitz, Dresden) in advanced cancer patients is a major focus.
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论文共 131 篇作者统计合作学者相似作者
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iScienceno. 9 (2023): 107585-107585
Mussarat Wahid, Benjamart Pratoomthai,Isioma U. Egbuniwe, Hannah R. Evans,Roya Babaei-Jadidi,Jason O. Amartey, Viola Erdelyi,Kiren Yacqub-Usman,Andrew M. Jackson,Jonathan C. Morris,Poulam M. Patel,David O. Bates
Cancer Immunology, Immunotherapyno. 12 (2023): 4001-4014
Shahd Talhouni,Wakkas Fadhil,Nigel P Mongan, Lara Field,Kelly Hunter,Sogand Makhsous,Alexandre Maciel-Guerra, Nayandeep Kaur, Ausrine Nestarenkaite,Arvydas Laurinavicius,Benjamin E Willcox,Tania Dottorini,
Frontiers in immunology (2023): 1057292
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