基本信息
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职业迁徙
个人简介
He received the American Pediatric Society/Society for Pediatric Research National Young Investigator Award in 2002; and is an active member of the American Society for Clinical Investigation and the American Pediatric Society.
RESEARCH
The Scharenberg laboratory is focused on the development of technology for engineering T-cells and hematopoetic stem cells:
1. Gene editing methods and technology: Our present efforts are centered on optimizing gene editing efficiency in primary T-cells and hematopoietic stem cells using viral vectors and advanced electroporation methods, and on developing gene edited cell products for hematopoietic genetic diseases and tolerance applications.
2. Synthetic biology: Next generation cell therapies require new approaches to provide physician control over cell survival, expansion, and potency. We are working on developing orthogonal receptor signaling systems that can be embedded in gene edited cell products to enable precise control over these characteristics.
3. Vector biology: we are working on developing synthetic vector systems for delivery of gene therapy and gene editing components both ex vivo and in vivo.
RESEARCH
The Scharenberg laboratory is focused on the development of technology for engineering T-cells and hematopoetic stem cells:
1. Gene editing methods and technology: Our present efforts are centered on optimizing gene editing efficiency in primary T-cells and hematopoietic stem cells using viral vectors and advanced electroporation methods, and on developing gene edited cell products for hematopoietic genetic diseases and tolerance applications.
2. Synthetic biology: Next generation cell therapies require new approaches to provide physician control over cell survival, expansion, and potency. We are working on developing orthogonal receptor signaling systems that can be embedded in gene edited cell products to enable precise control over these characteristics.
3. Vector biology: we are working on developing synthetic vector systems for delivery of gene therapy and gene editing components both ex vivo and in vivo.
研究兴趣
论文共 179 篇作者统计合作学者相似作者
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Laurent Poirot,Brian Philip,Cécile Schiffer-Mannioui, Diane Le Clerre,Isabelle Chion-Sotinel, Sophie Derniame, Pierrick Potrel, Cécile Bas, Laetitia Lemaire,Roman Galetto, Céline Lebuhotel,Justin Eyquem,
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