基本信息
浏览量:8
职业迁徙
个人简介
RESEARCH INTERESTS:
Andrej Sali’s laboratory develops and applies modeling methods for computing structures of biomolecular assemblies that are consistent with all available information from experimental methods, physical theories, statistical inference, and prior models. This integrative approach maximizes accuracy, precision, and completeness of the resulting models. The current version of the corresponding program, Integrative Modeling Platform (IMP), is being used to determine the structures of a number of macromolecular assemblies, in collaboration with experimentalists. Most prominently, the approach already enabled the determination of the configuration of the 550 proteins in the yeast Nuclear Pore Complex and 19 proteins in the 19S subunit of the 26S proteasome. This research was also a major contributing factor to the establishment of PDB-Development, the nascent worldwide Protein Data Bank archive for integrative structures. Finally, the integrative modeling approach is being expanded to the mapping of biomolecular networks and spatiotemporal modeling of entire cellular neighbourhoods.
研究兴趣
论文共 401 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Leah V. Schaffer, Mengzhou Hu,Edward L. Huttlin, Gege Qian, Abantika Pal,Neelesh Soni, Andrew Latham,Laura Pontano Vaites,Trang Le,Yue Qin,Christopher Churas,Dexter Pratt,
Cancer Researchno. 6_Supplement (2024): 2348-2348
bioRxiv : the preprint server for biology (2024)
Nature Structural & Molecular Biologypp.1-12, (2024)
Mengzhou Hu,Leah V. Schaffer,Edward L. Huttlin, Gege Qian, Andrew Latham, Abantika Pal,Laura Pontano Vaites,Trang Le,Yue Qin,Christopher Churas,Dexter Pratt,Robin Bachelder,
Cancer Researchno. 6_Supplement (2024): 6543-6543
Barak Raveh, Roi Eliasian, Shaked Rashkovits, Daniel Russel,Ryo Hayama, Samuel E Sparks,Digvijay Singh,Roderick Lim,Elizabeth Villa,Michael P Rout, David Cowburn,Andrej Sali
bioRxiv : the preprint server for biology (2024)
Eric T. Baldwin, Trevor van Eeuwen,David Hoyos, Arthur Zalevsky,Egor P. Tchesnokov, Roberto Sánchez, Bryant D. Miller,Luciano H. Di Stefano,Francesc Xavier Ruiz, Matthew Hancock, Esin Işik,Carlos Mendez-Dorantes,
Natureno. 7997 (2024): 194-206
Digvijay Singh,Neelesh Soni,Joshua Hutchings,Ignacia Echeverria, Farhaz Shaikh, Madeleine Duquette,Sergey Suslov,Zhixun Li,Trevor van Eeuwen,Kelly Molloy,Yi Shi,Junjie Wang,
bioRxiv : the preprint server for biology (2024)
Biocomputing 2024 (2024): 661-665
引用0浏览0WOS引用
0
0
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn