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Mechanistic Cell Biology
We investigate the molecular basis of cell division in eukaryotes. We are concerned with different aspects of the process of cell division, with specific topics ranging from the organization of the microtubule cytoskeleton, and most notably the mitotic spindle to the organization of centromeres and kinetochores. Our primary interest is to unveil the molecular mechanisms that drive these processes, so to be able eventually to manipulate them meaningfully. Most of our projects combine biochemical reconstitution with biophysical investigations and cellular analyses, so to provide testable mechanism-based hypotheses that allow making significant forays into the unknown. For this, we foster a broad methodological portfolio, which now includes classical methods in structural biology, mass spectrometry, biochemistry and biophysics and cell culture.
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论文共 135 篇作者统计合作学者相似作者
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Duccio Conti, Arianna Esposito Verza,Marion E. Pesenti,Verena Cmentowski,Ingrid R. Vetter,Dongqing Pan,Andrea Musacchio
biorxiv(2024)
Soumitra Polley,Tobias Raisch, Sabrina Ghetti, Marie Körner, Melina Terbeck,Frauke Gräter,Stefan Raunser,Camilo Aponte-Santamaría,Ingrid R. Vetter,Andrea Musacchio
Nature Structural & Molecular Biologypp.1-13, (2024)
Nature Structural & Molecular Biologyno. 1 (2024): 1-2
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Erica Di Cesare, Sara Moroni, Jessica Bartoli,Michela Damizia,Maria Giubettini, Carolin Koerner,Veronica Krenn,Andrea Musacchio,Patrizia Lavia
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