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In the viral recombination area, I completed studies unravelling the mechanisms of recombination in HIV and their interplay with selective pressure on the viral population. In addition, I contributed significantly to developing systems for the study of HCV recombination, revealing this virus capability for high frequency recombination. I had a major role in developing microscopy and bioinformatics systems to image and track HIV viral particles in real-time, which also allowed my investigations in HCV packaging and subcellular interactions. I also participated in collaborative studies investigating drug resistance development and neutralization of HCV in cell culture systems. More recently, I contributed microscopy data and analyses to studies of the novel SARS-CoV-2 pathogen. I have recently initiated cell culture based studies of HBV biology, including replication, antiviral resistance, and viral clearance.
研究兴趣
论文共 35 篇作者统计合作学者相似作者
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Alekxander Binderup,Andrea Galli,Nicolas Fossat,Carlota Fernandez-Antunez,Lotte S Mikkelsen, Lizandro René Rivera-Rangel,Troels K H Scheel,Ulrik Fahnøe,Jens Bukh,Santseharay Ramirez
Virology (2023): 179-185
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Karen A Gammeltoft,Yuyong Zhou, Carlos R Duarte Hernandez,Andrea Galli,Anna Offersgaard,Rui Costa,Long V Pham,Ulrik Fahnøe,Shan Feng,Troels K H Scheel,Santseharay Ramirez,Jens Bukh,
semanticscholar(2020)
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biorxiv(2020)
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