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Amy Howell is an Associate Research Scientist at the Marucci Center for Blueberry Cranberry Research. She has a background in plant science and pathology and her program targets utilizing cranberry for prevention and management of bacterial diseases, including urinary tract infections (UTIs), stomach ulcers, and periodontal disease. She is keen to have consumers utilize more natural alternative methods, such as cranberry for disease prevention in an effort to curb overuse of antibiotics and resistance development. Her primary research focus has been on isolating polyphenolic compounds from cranberry and determining their role in prevention of UTIs. She studies the pharmacokinetics and bioavailability of the structurally unique cranberry proanthocyanidins in an effort to determine site(s) of action and dose-response, as well as the influence of cranberry on enhancing the potency of antibiotics. She regularly collaborates in clinical trials on cranberry consumption and UTI prevention. Other projects include development of cranberry supplements for both human and canine urinary health, and anti-cancer, anti-viral and oral cavity health studies utilizing cranberry.
Howell is very involved in method development for powdered cranberry supplements, working closely with regulatory teams from AOAC and USP (US Pharmacopoeia) to determine standard methods for quantification of the bioactive compounds in cranberries. USP determines FDA-enforceable quality standards for drugs and dietary supplements. This is extremely important given the variability in efficacy and frequent adulteration of cranberry products.
Howell is very involved in method development for powdered cranberry supplements, working closely with regulatory teams from AOAC and USP (US Pharmacopoeia) to determine standard methods for quantification of the bioactive compounds in cranberries. USP determines FDA-enforceable quality standards for drugs and dietary supplements. This is extremely important given the variability in efficacy and frequent adulteration of cranberry products.
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bioRxiv : the preprint server for biology (2024)
Cancer Researchno. 7_Supplement (2023): 1745-1745
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Yun Zhang,Katherine M. Weh,Bridget A. Tripp,Jennifer L. Clarke,Connor L. Howard, Shruthi Sunilkumar,Amy B. Howell,Laura A. Kresty
Pharmaceuticalsno. 12 (2023): 1697
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JOURNAL OF DIETARY SUPPLEMENTSno. 3 (2023): 327-343
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