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Metalloproteins constitute one of the largest classes of proteins in the proteome and are involved in virtually every metabolic and signaling pathway of consequence to human health and disease. Broadly speaking, the Reddi laboratory is interested in determining the cellular, molecular, and chemical mechanisms by which metalloproteins are activated by cells, and once activated, how they communicate with other biomolecules to promote normal metabolism and physiology, placing an emphasis on systems relevant to cancer, neurodegenerative disorders, and infectious diseases. Current projects in the lab are focused on elucidating heme trafficking pathways and the role of Cu/Zn Superoxide Dismutase (SOD1) in redox signaling. Prospective students will get broad training in disciplines that span modern biochemistry, bioinorganic chemistry, biophysics, chemical biology, molecular genetics, and cell biology.
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论文共 57 篇作者统计合作学者相似作者
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Methods in molecular biology (Clifton, N.J.) (2023): 219-236
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Clinical Lymphoma Myeloma and Leukemia (2023): S148-S148
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Rebecca K Donegan, Yibo Fu,Jacqueline Copeland, Stanzin Idga,Gabriel Brown, Owen F Hale,Avishek Mitra,Hui Yang,Harry A Dailey,Michael Niederweis,Paras Jain,Amit R Reddi
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