Dr. Manges conducts research in molecular epidemiology, with particular focus on the role of the human intestinal microbiome in health. Her research group is currently investigating whether:
an agnostic, next generation metagenomic sequencing assay can be used to detect and characterize respiratory RNA viruses;
a sinonasal microbiota transfer (SNMT) can treat chronic sinusitis patients;
using microbiota transfer/transplant therapies can help to eradicate highly drug-resistant bacteria ('superbugs') from the body;
the intestinal microbiome contributes to infant undernutrition; and whether
cotrimoxazole treatment for HIV exposure/infection or malnutrition in children leads to long-term changes in the intestinal microbiome.