The main goal of her studies is to understand the role of genetic and environmental factors in the etiology of these cancers. Her studies combine epidemiologic, genetic, clinical, and molecular methodologies. Research Interests Identification of genetic and environmental risk factors for cancer Search for high-, moderate-, and/or low-risk cancer susceptibility genes using family-based, tumor-based, and case-control/cohort studies For cancers with identified major susceptibility gene mutations, investigation of other genetic and environmental factors and their interactions in the expression of disease