Alexander Treiber - Non-Clinical Drug Metabolism and Pharmacokinetics, Idorsia Pharmaceuticals Ltd

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论文共 75 篇作者统计合作学者相似作者

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The Orexin 1-Selective Receptor Antagonist Nivasorexant is a Time-Dependent Inhibitor of CYP2C19 and CYP3A4

Alexander Treiber, Fabienne Drouet, Swen Seeland, Florian Willecke,Jodi T Williams,Hamed Aissaoui, Benjamin Berger,Stephane Delahaye

Xenobiotica the fate of foreign compounds in biological systemspp.1-10, (2025)

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The Metabolism of the Orexin-1 Selective Receptor Antagonist Nivasorexant

Alexander Treiber,Swen Seeland, Belal Haschimi, Aude Weigel,Jodi T. Williams, Jerome Gabillet

Xenobiotica（2024）

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Evaluating the Efficacy of the Selective Orexin 1 Receptor Antagonist Nivasorexant in an Animal Model of Binge-Eating Disorder

Michel Alexander Steiner,Luca Botticelli,Giorgio Bergamini,Emanuela Micioni Di Bonaventura,John Gatfield,Jodi T. Williams,Alexander Treiber, Catherine Vaillant,Carlo Cifani,Maria Vittoria Micioni Di Bonaventura

INTERNATIONAL JOURNAL OF EATING DISORDERSno. 7 (2024): 1418-1432

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Reversible oxidation/reduction steps in the metabolic degradation of the glycerol side chain of the S1P₁ modulator ponesimod

Alexander Treiber,Swen Seeland,Jerome Segrestaa,Cyrille Lescop,Martin H. Bolli

XENOBIOTICA（2024）

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Pyrazole Derivatives As Selective Orexin-2 Receptor Antagonists (2-SORA): Synthesis, Structure-Activity-relationship, and Sleep-Promoting Properties in Rats

Christine Brotschi,Martin H. Bolli,John Gatfield,Catherine Roch,Thierry Sifferlen,Alexander Treiber,Jodi T. Williams,Christoph Boss

RSC MEDICINAL CHEMISTRYno. 1 (2024): 344-354

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Reversible oxidation/reduction steps in the metabolic degradation of the glycerol side chain of the S1P1 modulator ponesimod

Alexander Treiber,Swen Seeland,Jérôme Segrestaa,Cyrille Lescop,Martin H Bolli

Xenobiotica; the fate of foreign compounds in biological systemsno. 4 (2024): 182-194

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Reversible Oxidation/reduction Steps in the Metabolic Degradation of the Glycerol Side Chain of the S1P 1 Modulator Ponesimod

Alexander Treiber,Swen Seeland,Jérôme Segrestaa,Cyrille Lescop,Martin H. Bolli

Xenobioticano. 4 (2024): 182-194

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Discovery of Nivasorexant (ACT-539313): the First Selective Orexin-1 Receptor Antagonist (SO1RA) Investigated in Clinical Trials

Jodi T. Williams,Martin H. Bolli,Christine Brotschi,Thierry Sifferlen,Michel A. Steiner,Alexander Treiber,John Gatfield,Christoph Boss

Journal of Medicinal Chemistry（2024）

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Effect of Nivasorexant (ACT-539313), a Selective Orexin-1-receptor Antagonist, on Multiple Cytochrome P450 Probe Substrates in Vitro and in Vivo Using a Cocktail Approach in Healthy Subjects

Benjamin Berger,Priska Kaufmann,Matthias Berse,Alexander Treiber, Nathalie Grignaschi,Jasper Dingemanse

PHARMACOLOGY RESEARCH & PERSPECTIVESno. 5 (2023)

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The Metabolism of the Dual Orexin Receptor Antagonist Daridorexant

Alexander Treiber,Stephane Delahaye, Aude Weigel, Paivi Aeanismaa,John Gatfield,Swen Seeland

XENOBIOTICA（2023）

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