基本信息
浏览量:22
职业迁徙
个人简介
Research in the Howe Laboratory focuses on the mechanisms through which cells sense and interpret their extracellular environment and the signaling pathways through which these environmental cues control cell shape and cell movement. Our current interests include the role that the tissue microenvironment plays in the progression and spread of ovarian cancer. We use a variety of molecular and cellular techniques, with a particular emphasis on live-cell imaging, to investigate the pathways used by cells to sense the biochemical and mechanical properties of their extracellular matrix, and the interplay between mechanotransduction and classical second messenger signaling pathways in the regulation of cytoskeletal dynamics and invasive behavior. The lab also has burgeoning interests in using microfluidics and microfabrication to control the cellular microenvironment and in the development of novel methods for detecting protein-protein interactions.
研究兴趣
论文共 61 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Proceedings of the National Academy of Sciences of the United States of Americano. 13 (2024): e2314947121-e2314947121
Mingu Kang,Amanda J. Senatore, Hannah Naughton, Madeline McTigue, Rachel J. Beltman, Andrew A. Herppich,Mary Kay H. Pflum,Alan K. Howe
Journal of Biological Chemistrypp.107234-107234, (2024)
bioRxiv : the preprint server for biology (2023)
引用0浏览0WOS引用
0
0
Frontiers in Molecular Biosciences (2022): 953093-953093
Journal of Bone and Mineral Researchno. 8 (2019): 1546-1548
Signaling through Cell Abhesion Moleculespp.117-128, (2019)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn