Alan B. Sachs

Rosetta Inpharmatics, LLC, a Wholly Owned Subsidiary of Merck and Co., Inc., Seattle, WA 98109, USA

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Papers41 papers

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High Resolution Discovery Proteomics Reveals Candidate Disease Progression Markers of Alzheimer's Disease in Human Cerebrospinal Fluid

Ronald C Hendrickson,A Y Lee, Qingkun Song,Andy Liaw,Matthew C Wiener,Cloud P Paweletz, J Seeburger,Jing Li,Fanhao Meng,Ekaterina G Deyanova,Matthew T Mazur,Robert E Settlage

PLOS ONE, (2015)

Cited by20Bibtex

RISC bound siRNA is a determinant of RNAi mediated gene silencing in mice

Jie Wei, Jeffrey Jones, Jing Kang, Ananda Card, Michael Krimm,Paula J Hancock, Yi Pei,Brandon Ason, Elmer Payson, Natalya Dubinina,Mark T Cancilla, Mark Stroh

Molecular Pharmacology, (2011)

Cited by39Bibtex

Application of an end-to-end biomarker discovery platform to identify target engagement markers in cerebrospinal fluid by high resolution differential mass spectrometry

Cloud P Paweletz,Matthew C Wiener,Andrey Y Bondarenko,Nathan A Yates,Qinghua Song,Andy Liaw,Anita Y H Lee,Brandon T Hunt,Ernst S Henle,Fanyu Meng,Holly Funk Sleph,Marie Holahan

Journal of proteome research, no. 3 (2010): 1392-1401

Cited by46WOSBibtex

Evaluation of Efficacy, Biodistribution, and Inflammation for a Potent siRNA Nanoparticle: Effect of Dexamethasone Co-treatment

Marc T Abrams,Martin L Koser,Jessica Seitzer,Stephanie C Williams,Martha A DiPietro,Weimin Wang,Andrew W Shaw,Xianzhi Mao,Vasant Jadhav,Joseph P Davide,Paul A Burke,Alan B Sachs

Molecular therapy : the journal of the American Society of Gene Therapy, no. 1 (2010): 171-180

Cited by81WOSNATUREBibtex

Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels (vol 86, pg 505, 2005)

Alessandra C. Cervino,Guoya Li, Steve Edwards,Jun Zhu,Cathy Laurie,George Tokiwa,Pek Yee Lum,Susanna Wang,Lawrence W. Castellani,Aldons J. Lusis,Sonia Carlson,Alan B. Sachs

Genomics, (2009)

Bibtex

Corrigendum to “Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels” [Genomics 86 (2005) 505–517]

Alessandra C. Cervino,Guoya Li,Steve Edwards,Jun Zhu,Cathy Laurie,George Tokiwa,Pek Yee Lum,Susanna Wang,Lawrence W. Castellani,Aldons J. Lusis,Sonia Carlson,Alan B. Sachs

Genomics, no. 4 (2009): 399-399

Cited by2EIBibtex

Denise M. Kenski

Denise M Kenski, A Cooper, J J Li,Aarron T Willingham,Henry J Haringsma, T A Young,Nelly A Kuklin, Jeffrey Jones,Mark T Cancilla,Daniel R Mcmasters,Melina Mathur,Alan B Sachs

(2009)

Bibtex

Sequence variation in NPC1L1 and association with improved LDL-cholesterol lowering in response to ezetimibe treatment

Jason S. Simon,Maha C. Karnoub,David J. Devlin,Maria G. Arreaza,Ping Qiu,Stephanie A. Monks,Michael E. Severino,Paul Deutsch,Joanne Palmisano,Alan B. Sachs,Marvin L. Bayne,Andrew S. Plump

Genomics, no. 6 (2005): 648-656

Cited by96EIWOSBibtex

Integrating genotypic, molecular profiling, and clinical data to elucidate common human diseases

Eric E Schadt,Alan B Sachs

(2005)

Bibtex

Skin biopsies for the measurement of clinical pharmacodynamic biomarkers

Robert L Phillips,Alan B Sachs

Current Opinion in Biotechnology, no. 6 (2005): 687-690

Cited by9EIWOSBibtex

Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels

Alessandra C. Cervino,Guoya Li,Steve Edwards,Jun Zhu,Cathy Laurie,George Tokiwa,Pek Yee Lum,Susanna Wang,Lawrence W. Castellini,Aldons J. Lusis,Sonia Carlson,Alan B. Sachs

Genomics, no. 5 (2005): 505-517

Cited by140EIWOSBibtex

The tobacco mouse and its relatives: a 'tail' of coat colors, chromosomes, hybridization

Nadine K Kolas, Li Yuan, I A Zalenskaya,Luca Gentile,Manuela Monti, Sebastiano, Merico,Raffaella Nicolai,Menotti Calvani,Silvia Garagna,Carlo Alberto Redi,Maurizio Zuccotti

(2004)

Bibtex

Ribosome Loading onto the mRNA Cap Is Driven by Conformational Coupling between eIF4G and eIF4E

John D. Gross,Nathan J. Moerke,Tobias von der Haar,Alexey A. Lugovskoy,Alan B. Sachs,John E.G. McCarthy,Gerhard Wagner

Cell, no. 6 (2003): 739-750

Cited by320EIWOSBibtex

Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E. [Editor's Choice, Science, 303, 09 January 2004]

John D Gross,Nathan J Moerke, Von Der Haar T, Alexey Lugovskoy,Alan B Sachs, J E Mccarthy,Gerhard Wagner

(2003)

Bibtex

Development and characterization of a reconstituted yeast translation initiation system

MIKKEL A. ALGIRE,DAVID MAAG,PETER SAVIO,MICHAEL G. ACKER,SALVADOR Z. TARUN,ALAN B. SACHS,KATSURA ASANO,KLAUS H. NIELSEN,DEANNE S. OLSEN,LON PHAN,ALAN G. HINNEBUSCH,JON R. LORSCH

Rna-a Publication of The Rna Society, no. 3 (2002): 382-397

Cited by9WOSBibtex

One-step affinity purification of the yeast ribosome and its associated proteins and mRNAs

Toshifumi Inada,Eric Winstall,Salvador Z Tarun,John R Yates,Dave Schieltz,Alan B Sachs

RNA (New York, N.Y.), no. 7 (2002): 948-958

Cited by106WOSBibtex

Cell Cycle–Dependent Translation InitiationIRES Elements Prevail

Alan B Sachs

Cell, no. 3 (2000): 243-245

Cited by11Bibtex

The yeast nuclear cap binding complex can interact with translation factor eIF4G and mediate translation initiation

Puri Fortes,Toshifumi Inada,Thomas Preiss,Matthias W Hentze,Iain W Mattaj,Alan B Sachs

Molecular cell, no. 1 (2000): 191-196

Cited by109WOSEIBibtex

Cell Cycle–Dependent Translation Initiation

Alan B Sachs

Cell, no. 3 (2000): 243-245

EIBibtex

Decapping of stabilized, polyadenylated mRNA in yeastpab1 mutants

John P. Morrissey,Julie A. Deardorff,Clarissa Hebron,Alan B. Sachs

Yeast, no. 8 (1999): 687-702

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