Currently focused on clinical outcomes research, systematic reviews and meta-analyses of cohort studies and randomized controlled trials, clinical practice guidelines using GRADE methodology, and administrative claims database analyses.

Topics of expertise in clinical research are cardiovascular diseases (acute coronary syndromes, heart failure, atrial fibrillation, diabetes, obesity, vascular/cardiac surgery), novel oral anticoagulants, venous thromboembolism, peri-operative medicine, obstructive sleep apnea, and HIV-associated infections.

Editor of the Cochrane Heart Group, Deputy Statistical Editor of the J Thor Cardiovasc Surg, and Academic Editor of PLoS One. He is reviewer for Heart, Ann Intern Med, CID, Int J Cardiol, Eur Heart J, JAMA Intern Med, J Clin Epidemiol, Diabetic Med, Cochrane Heart Group, J Thorac Cardiovasc Surg, The Lancet, Thrombosis & Haemostasis, BMJ, Thrombosis J and Diabetologia.