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Transdermal and topical drug delivery projects research formulation, bioavailability and distribution of topically applied medicaments. We have developed targeted delivery systems which release drugs in response to biological stimuli, in particular to exploit the changed physiology in many skin diseases (e.g. enzymes or pH) to trigger drug release at the specific diseased sites. Further research projects are exploring the penetration of large macromolecules into and through human skin and the use of polymeric carrier systems to retain drugs within the tissue. Other recent projects have investigated strategies to increase drug delivery to and through the skin using, for example, penetration enhancers, supersaturated systems or colloidal carriers.
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Vitamin B Complex [Working Title] (2023)
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IntechOpen eBooks (2023)
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B-Complex Vitamins - Sources, Intakes and Novel Applications (2022)
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