Adam M. Gilbert - Exploratory Medicinal Chemistry, Chemical and Screening Sciences, Wyeth Research

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论文共 68 篇作者统计合作学者相似作者

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Applications of Contemporary Tools to Measure Plasma Protein Binding of Targeted Protein Degraders

Mark Niosi, Sam Zhang, Woodrow Burchett, Carley J S Heck, Gilles H Goetz, James J Federico, Steven Gernhardt,Samantha Jordan,Adam M Gilbert, Matthew F Calabrese, R Scott Obach, Stefanus J Steyn

Drug metabolism and disposition the biological fate of chemicalsno. 5 (2025): 100066-100066

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Expanding the Ligandable Proteome by Paralog Hopping with Covalent Probes

Yuanjin Zhang,Zhonglin Liu, Marsha Hirschi,Oleg Brodsky,Eric Johnson,Sang Joon Won,Asako Nagata,Matthew D Petroski,Jaimeen D Majmudar,Sherry Niessen,Todd VanArsdale,Adam M Gilbert,Matthew M Hayward,Al E Stewart,Andrew R Nager,Bruno Melillo,Benjamin Cravatt

bioRxiv the preprint server for biology (2024)

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Abstract LB028: Discovery and Characterization of Selective Heterobifunctional Degraders of EP300 in Hematopoietic Malignancies

Frederick A. Derheimer, Ninvita Givarkes,Natalie Miller, Rita Grantner, Casey Quinlan, Sonja Brun,Thomas Paul,Astrid Ruefli-Brasse,Stefan Steyn,Derek Bartlett,Matthew Hayward,Matthew Brown,Daniel Uccello, Benjamin J. Burke,Kris Borzilleri,Adam Gilbert,Michelle Hemkens

CANCER RESEARCH（2024）

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An Allosteric Cyclin E-CDK2 Site Mapped by Paralog Hopping with Covalent Probes

Yuanjin Zhang,Zhonglin Liu, Marscha Hirschi,Oleg Brodsky,Eric Johnson,Sang Joon Won,Asako Nagata, Divya Bezwada,Matthew D. Petroski,Jaimeen D. Majmudar,Sherry Niessen,Todd Vanarsdale,Adam M. Gilbert,Matthew M. Hayward,Al E. Stewart,Andrew R. Nager,Bruno Melillo,Benjamin F. Cravatt

NATURE CHEMICAL BIOLOGY (2024)

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Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M4 Muscarinic Acetylcholine Receptor

Journal of Medicinal Chemistryno. 13 (2024): 10831-10847

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Translational PK-PD for Targeted Protein Degradation

Derek W. Bartlett,Adam M. Gilbert

Chemical Society reviews（2022）

引用27浏览0WOS引用

A Kinetic Proofreading Model for Bispecific Protein Degraders

Bartlett Derek W.,Gilbert Adam M.

Journal of Pharmacokinetics and Pharmacodynamics（2020）

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Snapshots and Ensembles of BTK and Ciap1 Protein Degrader Ternary Complexes

James Schiemer,Reto Horst,Yilin Meng,Justin I. Montgomery,Yingrong Xu,Xidong Feng,Kris Borzilleri,Daniel P. Uccello,Carolyn Leverett,Stephen Brown,Ye Che,Matthew F. Brown,Matthew M. Hayward,Adam M. Gilbert,Mark C. Noe,Matthew F. Calabrese

Nature Chemical Biology（2020）

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Synthesis Of Selective Jak3 Inhibitor Pf-06651600: Discovery To Early Clinical Supplies

John Trujillo,Yong Tao,Neal Sach,Sidney Liang, Kristin Wiglesworth,Teresa Makowski,Brian Samas,Kevin Girard,Jason Mustakis, Peter Rose, James Mcwilliams,Ruchi Mehta,Agustin Casimiro-Garcia,Atli Thorarensen,Jean-Baptiste Telliez,Matthew Brown,Adam Gilbert, Matt Hayward,Jonathan Langille,Justin Montgomery,Ray Unwalla,Felix Vajdos

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY (2019)

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