基本信息
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个人简介
Prof Pandit's research program utilises foundation platform technologies to drive disruptive change through a synergistic network of national and international academic, clinical and industrial collaborations. They develop hierarchical biomaterial constructs coupled with tailored functionalisation strategies. Biochemical functionalisation with carbohydrates, nucleic acids, antibodies and peptides are designed to influence fundamental physiological processes with high potency and selectivity. Prof Pandit develops functional, biocompatible building blocks encompassing synthetic and natural polymers, tailored glycomolecules, small molecules nucleic acids targeting systems and cellular elements. These platforms include targeted controlled-drug-release systems and multi-component biomaterial-based selective delivery systems and the synthesis of electrically responsive materials, cyclic polymers and functional branched poly(amino acid) as well as peptidomimetics and glycan conjugates. These macromolecular complexes form functional interfaces between implanted devices and biological systems to endow the former with bio-responsiveness and/or biological function. In addition, hierarchically assembled micro- and nano-structured implants and devices are designed to emulate fundamental cellular architecture and offer control over cellular function, enable cell phenotype maintenance, enhance matrix deposition and facilitate acceptance and clinical translation of cell-based devices. These platforms have been developed for musculoskeletal, cardiovascular, soft tissue repair and neural targets with a number of others targets currently under investigation.
研究兴趣
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Giulia Comini,Rachel Kelly,Sarah Jarrin, Tommy Patton, Kaushik Narasimhan,Abhay Pandit,Nicola Drummond,Tilo Kunath,Eilis Dowd
Kieran Joyce, Aert F Scheper, Aung Myat Phyo, Roisin O'Flaherty,Richard Drake,Aiden Devitt,Martina Marchetti-Deschmann,Radka Saldova,Abhay Pandit
crossref(2024)
Journal of tissue engineering (2024): 20417314231203824-20417314231203824
Analytical chemistry (2024)
Molecular pharmaceuticsno. 4 (2024): 1609-1624
Journal of Tissue Engineering (2024)
FASEB JOURNALno. 12 (2023): e23272-e23272
TISSUE ENGINEERING PART Ano. 13-14 (2023)
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Trends in molecular medicineno. 2 (2023): 178-196
Biotechnology Advances (2023): 108184
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