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RESEARCH INTERESTS
Angela Vincent's major research interests included all auto-antibody mediated ion channel and receptor disorders of the nervous system. Specific achievements included:
The discovery that maternal antibodies to different fetal proteins can cause rare neuromuscular disorders, and are likely to be involved in some forms of autism or other neurodevelopmental disorders.
The definition and characterisation of a new form of myasthenia gravis associated with antibodies to a receptor tyrosine kinase, MuSK, that performs an important maintenance role at the neuromuscular junction.
The recognition that some central nervous system disorders, involving memory loss, seizures, movement disorders and psychiatric features, can be caused by antibodies to various receptors or ion channel associated proteins. In these, and several other conditions, she helped to devise new ways to measure the pathogenic antibodies for better clinical diagnosis, and established in vitro and in vivo model systems for investigation of the pathophysiology of the diseases.
研究兴趣
论文共 1222 篇作者统计合作学者相似作者
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Nature communicationsno. 1 (2024): 2918-2918
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Biographical Memoirs of Fellows of the Royal Society (2023): 93-107
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Social Science Research Networkno. 8 (2023): e0282645-e0282645
Nature communicationsno. 1 (2023): 8487-8487
RRNMF Neuromuscular journalno. 3 (2023)
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Brain : a journal of neurology (2023)
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, Simon Nadel,Claire Cameron,David Pace,Rachel Kneen, Matilda Hill,Federico Martinón-Torres,Tom Solomon,Mandy Wan,Angela Vincent, Michael Absoud,Patrick Waters,
BMJ Openno. 11 (2023): e072134-e072134
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