Astrid Vallès - Departament de Biologia Cellular de Fisiologia i d'Immunologia, Unitat de Fisiologia Animal, Universitat Autònoma de Barcelona, Barcelona, Spain

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Erratum: Proof-of-concept study for liver-directed miQURE technology in a dyslipidemic mouse model

Vanessa Zancanella,Astrid Vallès,Jolanda M P Liefhebber,Lieke Paerels, Carlos Vendrell Tornero, Hendrina Wattimury, Tom van der Zon, Kristel van Rooijen, Monika Golinska, Tamar Grevelink,Erich Ehlert,Elsbet Jantine Pieterman,

Molecular therapy. Nucleic acidsno. 2 (2024): 102189-102189

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AAV5-miHTT gene therapy mediates sustained mutant huntingtin lowering in brain and cerebrospinal fluid of Huntington's disease minipigs up to 5 years

L. van der Bent, C. Brouwers,A. Stam, L. Spronck, J. Klima, J. Juhasova, B. Levinska,S. Juhas, J. Motlik,M. Evers, Z. Ellederova,A. Valles

MOVEMENT DISORDERS (2023): S386-S386

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Proof-of-concept study for liver-directed miQURE technology in a dyslipidemic mouse model

Vanessa Zancanella,Astrid Valles,Jolanda M. P. Liefhebber,Lieke Paerels, Carlos Vendrell Tornero, Hendrina Wattimury, Tom van der Zon,Kristel van Rooijen,Monika Golinska, Tamar Grevelink,Erich Ehlert,Elsbet Jantine Pieterman,

MOLECULAR THERAPY-NUCLEIC ACIDS（2023）

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Combining Vectorized Antibody and miRNA Lowering Strategies for Synucleinopathies

Seya Acar-Broekmans, Rhode Erbrink, Nikki Timmer, Charlot Van Rooijen, Sebastian Kieper, Verena Hehle,Astrid Valles

MOLECULAR THERAPYno. 4 (2023): 708-708

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Development of an alpha-Synuclein Targeting Vectorized Antibody Strategy: First In Vivo Proof of Mechanism in Wild Type Mice

Seya Acar-Broekmans, Rhode Erbrink, Charlot Van Rooijen,Lukas K. Schwarz, Meriem Bourajjaj, Laura Tade, Verena Hehle,Astrid Valles

MOLECULAR THERAPYno. 4 (2023): 494-494

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Alpha-Synuclein Lowering and Rescue of Motor Phenotype by miRNA-Based AAV Gene Therapy in In Vivo Parkinson's Disease Models

Seyda Acar Broekmans, Carlos Vendrell Tornero,Lodewijk Toonen, Mercedes Valls, Rhode Erbrink, Kaila E. Ronde,Wytse Hogewerf, Lisette E. D. Tolsma,Renee I. Seinstra, Leen L. S. Janssen,Ellen A. A. Nollen,Astrid Valles

MOLECULAR THERAPY（2022）

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Emerging Therapies for Huntington's Disease - Focus on N-Terminal Huntingtin and Huntingtin Exon 1

M Leontien van der Bent,Melvin M Evers,Astrid Vallès

BIOLOGICS-TARGETS & THERAPY（2022）

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Functional Intercellular Transmission of miHTT via Extracellular Vesicles: An In Vitro Proof-of-Mechanism Study

Roberto D V S Morais,Marina Sogorb-González,Citlali Bar,Nikki C Timmer,M Leontien Van der Bent,Morgane Wartel,Astrid Vallès

CELLS（2022）

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MiRNA-Mediated Knockdown of ATXN3 Alleviates Molecular Disease Hallmarks in a Mouse Model for Spinocerebellar Ataxia Type 3

Rui Jorge Nobre,Diana D Lobo,Carina Henriques,Sonia P Duarte,Sara M Lopes,Ana C Silva,Miguel M Lopes,Fanny Mariet,Lukas K Schwarz, M S Baatje,Valerie Ferreira,Astrid Vallès,

NUCLEIC ACID THERAPEUTICS（2022）

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Aav5-mihtt gene therapy mediates sustained mutant huntingtin lowering in brain and cerebrospinal fluid of huntington disease minipigs up to 4 years

Leontien Van der Bent,Cynthia Brouwers,Robin Pocornie,Anouk Stam,Steffi Jonk,Jiri Klima,Stefan Juhas,Jan Motlik,Melvin Evers,Zdenka Ellederovae,Astrid Valles

I: Experimental therapeutics – preclinical (2022): A86-A86

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