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Dr. Jaffe's initial efforts focused on coagulation and fibrinolysis and resulted in an appreciation for the pro-coagulant effects of plasminogen activators. At that time, he was also actively involved in defining how to best measure and use CKMB to determine the diagnosis and prognosis (infarct size) of patients with acute myocardial infarction.
Subsequently, with investigators at Washington University, he helped to develop and was responsible for the validation studies of the first cardiac troponin I assay. His efforts have since focused on the measurement of cardiac troponin and how to use the value obtained from clinical studies.
In addition, he has expanded his interests into the area of heart failure and has published extensively on the use of both cardiac troponin and natriuretic peptides to characterize patients with both acute and chronic heart failure. An additional interest relates to the intersection of depression and heart disease where he was the co-chair of the Enhancing Recovery in Coronary Heart Disease (ENRICHD) study of post-acute myocardial infarction patients.
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论文共 98 篇作者统计合作学者相似作者
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L. De Michieli,O. F. Abouezzeddine, M. A. Abbasi, D. R. Davies, C. G. Scott,E. Muchtar,A. Dispenzieri,M. Grogan,M. Redfield,A. S. Jaffe
European Heart Journalno. Supplement_2 (2023)
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Barbara R. Kelley,Amy M. Wockenfus,Brooke M. Katzman,Grant M. Spears,Brad S. Karon,Allan S. Jaffe,Leslie J. Donato
Clinical Chemistryno. Supplement_1 (2023)
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European Journal of Preventive Cardiologyno. Supplement_1 (2023)
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Clinical Chemistryno. Supplement_1 (2023)
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