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个人简介
His research employs microfluidics for high-throughput biological applications. He has developed microfluidic methods to create emulsions that consist of droplets of very precise and consistent sizes and to manipulate the processing and contents of individual droplets in different ways. The droplets are used to create micro-compartments, which can be loaded with single cells and other active materials, such as drugs, nutrients, and assay reagents. By chaining together different microdevice components, the droplets can be used as tiny "test tubes" for performing chemical and biological reactions. This allows multiple, independent reactions to take place at the rate of thousands per second, while using minuscule amounts of total reagent. Adam is using this approach for directed evolution, genetic sequencing, and cell sorting.
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论文共 230 篇作者统计合作学者相似作者
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bioRxiv : the preprint server for biology (2024)
Harish N. Vasudevan,Emily Payne,Cyrille L. Delley,S. John Liu,Kanish Mirchia,Matthew J. Sale,Sydney Lastella, Maria Sacconi Nunez,Calixto-Hope G. Lucas, Charlotte D. Eaton, Tim Casey-Clyde, Stephen T. Magill,
Xiangpeng Li,Linfeng Xu,Benjamin Demaree,Cecilia Noecker,Jordan E. Bisanz, Daniel W. Weisgerber,Cyrus Modavi,Peter J. Turnbaugh,Adam R. Abate
biorxiv(2024)
NATURE BIOTECHNOLOGY (2023)
Iain C. Clark,Prakriti Mudvari,Shravan Thaploo,S Abigail Smith, Mohammad Abu‐Laban,Mehdi S. Hamouda,Marc Theberge,Sakshi Shah,Sung Hee Ko,Liliana Pérez, Daniel Bunis,James S. Lee,
Nature Reviews Methods Primersno. 1 (2023): 1-22
Iain C. Clark,Kristina M. Fontanez,Robert H. Meltzer,Yi Xue,Corey Hayford,Aaron May-Zhang, Chris D'Amato,Ahmad Osman,Jesse Q. Zhang,Pabodha Hettige, Jacob S. A. Ishibashi,Cyrille L. Delley,
Preeti Yadav, Javier Gómez Ortega,Kai-chun Chang, Sixuan Pan, Nivedita Biswas,Julia Nilsson,Xiaoyang Yin,Aritra Bhattacharyya,Kaveh Boostanpour,Tatsuya Tsukui,Dean Sheppard,Baosheng Li,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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NATURE REVIEWS METHODS PRIMERSno. 1 (2023)
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