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The goal of the Berger laboratory is to enable precision medicine by systematically uncovering the molecular alterations in cancer, determining the function of these variant alleles, and understanding how these alleles modulate response to targeted or immune-based therapies. Although many of the genes involved in cancer have now been identified, a major challenge is discovering which specific alleles of these genes are involved and how these alleles modulate therapeutic response. We combine functional genomics, computational biology, biochemistry, and genetics to understand the mechanism of somatic cancer variants. Our goal is to identify drug targets and biomarkers and to translate this knowledge into clinical benefit for patients.
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论文共 103 篇作者统计合作学者相似作者
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Siobhan O'Brien,Alice H. Berger
Cancer Researchno. 6_Supplement (2024): 2932-2932
crossref(2023)
Cancer Researchno. 7_Supplement (2023): 2628-2628
CANCER RESEARCHno. 7 (2023)
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Molecular Cancer Researchno. 5_Supplement (2023): B028-B028
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MOLECULAR CANCER RESEARCHno. 5 (2023)
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Amanda K Riley, Michael Grant, Aidan Snell,Athea Vichas,Sitapriya Moorthi,Anatoly Urisman,Pau Castel,Lixin Wan,Alice H Berger
bioRxiv : the preprint server for biology (2023)
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